Archive
Results for International Research Highlight
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International Research HighlightReviewing rapid COVID-19 tests
November 22, 2021
Point-of-care tests offer speed and practicality over lab-based PCR testing, with some caveats.
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International Research HighlightExisting drugs may help with COVID-19 treatment
October 18, 2021
Computational screening of SARS-CoV-2 genomes identified several proteins which could be targeted by existing drugs to treat COVID-19
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International Research HighlightCombined therapy boosts kidney cancer survival rates
October 7, 2021
A global phase 3 clinical trial demonstrates the efficacy of a novel combined therapy for advanced kidney cancer
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International Research HighlightA dynamic duo to fight MERS
September 30, 2021
Experiments in mice suggest that a two-antibody cocktail could prevent infection with the Middle East respiratory syndrome coronavirus.
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International Research HighlightHow melanoma manipulates its way to metastasis
September 16, 2021
A growth factor secreted by melanoma cells makes the immune system ignore metastasis
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International Research HighlightNanotechnology prevents preterm birth in mice
August 5, 2021
Formulation helps overcome mucus barriers for targeted drug delivery
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International Research HighlightOptimizing influenza vaccines to harness pre-existing immunity
July 22, 2021
Understanding how immune cells respond to natural infection compared with vaccination demonstrates how vaccines could broader immunity
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International Research HighlightCOVID-19 impact does not end with hospital discharge
July 8, 2021
Hospital discharge could still mean a long way to full recovery for severe COVID-19 patients
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International Research HighlightDNA sequencing accelerates infection diagnosis
July 1, 2021
Detection of pathogenic genetic material in body fluids could speed up treatment of serious infections
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International Research HighlightA fatty diet disturbs circadian brain metabolism
June 24, 2021
A high-fat diet changes metabolic oscillations in brain regions that control circadian rhythms.
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International Research HighlightAI-supported decision-making improves skin cancer diagnosis
May 5, 2021
Researchers showcase a framework for image-based AI systems to assist doctors deliver more accurate diagnoses.
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International Research HighlightCheaper, better screening of type 1 diabetes in high-risk children
February 24, 2021
A low-cost model combining genetic, clinical, and immunological risk factors could help predict type 1 diabetes
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International Research HighlightReducing the STING of cancer therapy
February 18, 2021
Packaging cancer therapy within injectable microcubes mitigates the need for multiple invasive treatments
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International Research HighlightAI algorithms for rapid coronavirus diagnosis
February 3, 2021
Researchers use advanced deep learning models to create an AI system that can help identify COVID-19 in minutes.
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International Research HighlightInvestigating COVID-19 immune responses
January 20, 2021
An in-depth analysis of the COVID-19 immune response offers new tools to clinicians.
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International Research HighlightUncovering trends in antibiotic consumption
January 6, 2021
Study assesses global antibiotic consumption patterns over a 15-year period.
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International Research HighlightMeasuring the risk of contracting latent tuberculosis in clinical training
December 23, 2020
Medical students face a greater risk of being infected with TB bacteria than trainees in other specializations
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International Research HighlightFinding the correct warfarin dose for Saudi patients
December 9, 2020
A pharmacogenetics study involving a cohort of Saudi recipients of the drug warfarin provides valuable insights into dosing and effectiveness
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International Research HighlightGut microbe transplant treats graft versus host disease
December 2, 2020
Faecal bacteria from healthy donors can save the lives of blood stem cell transplant recipients
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International Research HighlightProfiling a rare genetic disorder
November 25, 2020
A deep dive into data about a rare amino acid deficiency points the way towards early diagnosis and drug discovery
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International Research HighlightHair-growing skin produced from human stem cells
November 18, 2020
Complete skin-in-a-dish tissue offers new options for wound healing, genetic skin conditions and baldness.
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International Research HighlightT cells recognize the COVID-19 virus before and after infection
November 11, 2020
SARS-CoV-2 triggers a strong T cell-based immune response, but many people already have some cross-reactive immune memory
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International Research HighlightPinning down a genetic cause of increased prostate cancer risk
November 4, 2020
Propensity hinges on the regulatory role of a rare genetic variant
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International Research HighlightFinding genetic leads for severe coronavirus cases
October 28, 2020
Respiratory failure in some COVID-19 patients could be associated to their genetic profile.
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International Research HighlightNew gene database to inform bespoke treatments
October 21, 2020
A global reference showing the variation of immune system genes across populations will improve personalized medicine and transplant outcomes.
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International Research HighlightSupercharged immune cells to fight lymphoma
July 7, 2020
An immunotherapy approach, based on adapting a patient’s immune cells to tackle specific cancer cells, shows promise against rare lymphoma.
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International Research HighlightStem cell therapy: Insights into heart repair mechanisms
April 21, 2020
The injection of stem cells into the heart following cardiac arrest induces an innate immune response that helps repair damaged tissues.
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International Research HighlightArtificial intelligence enhances in-surgery tumour analysis
April 5, 2020
An automated system can provide diagnostic information during surgery for a brain tumour with a similar accuracy to pathologists.
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International Research HighlightA mother’s protective gift to pre-term babies
March 10, 2020
Preterm babies have a similar arsenal of maternal antibodies to those of full-term babies, suggesting that their higher infection risk is due to other factors.
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International Research HighlightBirth weight estimates updated
January 23, 2020
New research provides more accurate charts for assessing birth weight based on updated information to identify need for infant care
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International Research HighlightThe mental toll of conflict
January 23, 2020
Updated WHO estimates show mental disorders are three times more common in conflict settings.
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International Research HighlightA rocking good sleep
January 12, 2020
Study reveals that the gentle rocking motion that soothes children to sleep works just as well for adults, and also keeps their memory strong.
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International Research HighlightWearing diabetes care lightly
December 30, 2019
A new wearable, flexible nanosensor could help monitor glucose levels without the need for blood tests
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International Research HighlightAn instigator for immunodeficiency
December 8, 2019
A genomic survey of immunodeficient patients reveals a gene with an important role in fending off infection and controlling inflammation
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International Research HighlightWhat doesn’t kill your ancestors makes you stronger
December 1, 2019
Stressed-out fence lizards inadvertently give younger generations a better chance against predators.
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International Research HighlightSlim chance of defying genetic odds in the weight game
November 17, 2019
Staying thin may not be the result of sheer willpower. A new study shows that maintaining a healthy weight can come down to genetics.
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International Research HighlightHeartening findings on an aortic surgery alternative
November 10, 2019
A minimally invasive alternative to heart surgery may offer better outcomes for treating a broader range of patients with aortic stenosis
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International Research HighlightBrains of blind people adapt to sharpen sense of hearing
November 6, 2019
People with impaired vision have sharpened and nuanced sense of hearing.
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International Research HighlightRotavirus vaccine could help prevent type 1 diabetes
October 1, 2019
Rotavirus vaccine is showing a correlation with a reduction in type 1 diabetes incidents among infants.
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International Research HighlightRevealing the missing heritability of colorectal cancer
July 21, 2019
Diagnosis of colorectal cancer may improve following the discovery of two gene mutations.
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International Research HighlightHeart disease: Link with air pollution spikes in China
July 14, 2019
A study covering 26 large cities in China links short-term exposure to air pollution with increased hospital admissions for heart failure.
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International Research HighlightTargeting hepatitis B virus vulnerabilities
July 8, 2019
Metabolic pathways altered by chronic hepatitis B virus infection may give clues to novel treatment.
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International Research HighlightAn effective solution for marrow transplantation
July 1, 2019
A combination of young and adult donor stem cells offers robust, safe treatment for lymphoma patients lacking closely matching donors.
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International Research HighlightTrimming the stomach lining to fight fat
June 26, 2019
Research suggests that targeting the stomach lining may alleviate obesity.
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International Research HighlightColorectal cancer: Overweight young people at risk
June 9, 2019
Being overweight before the age of 30 may increase the chances of developing colon cancer later in life.
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International Research HighlightProfiling the evolution of breast cancer cells
June 2, 2019
Genetic profiling of breast cancer metastases provides insight that could help improve treatment.
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International Research HighlightUncovering the drivers of primary tumour growth
May 26, 2019
Key proteins could contribute to much earlier cancer progression than previously thought.
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International Research HighlightMultiple sclerosis: An exercise in brain protection
May 19, 2019
Exercise for people with multiple sclerosis protects against degeneration and improves physical function.
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International Research HighlightThe immune sting of WASp
May 12, 2019
A protein implicated in a range of immune diseases proves essential for proper T-cell development.
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International Research HighlightDangerous trends in worldwide childhood obesity
March 24, 2019
There are more underweight than obese children in the world, but the balance could change in just five years.
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International Research HighlightBreakthrough in bone marrow mapping
March 10, 2019
New 3D imaging shows how cells, tissues and proteins are distributed within bone marrow.
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International Research HighlightObesity and diabetes: Heading for the fast burn
March 3, 2019
Incorporating periods of fasting into diets shows potential as a means of halting the progression of metabolic diseases.
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International Research HighlightGenetic make-up and its impact on viral infection
February 12, 2019
A fast and simple approach for analysing people’s genetic make-up and the viruses that infect them could reveal molecular information that can be used to improve prevention and treatment of disease.
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International Research HighlightInvestigating immune responses
February 12, 2019
A molecule produced by hepatitis B virus prompts the body’s immune cells to leap into action.
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International Research HighlightLoss of synaptic ‘caretaker’ leads to fatal infant brain injury
February 11, 2019
A rare genetic mutation that impairs communication between neurons could provide insight into Alzheimer’s and Parkinson’s.
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International Research HighlightIn search of strategies to disrupt viral docking
February 11, 2019
Insights into how two viruses initiate the infection of host cells could guide development of countermeasures.
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International Research HighlightImproving stem cell donation
February 10, 2019
Stem cells could be collected from donors more safely by using a less invasive catheter.
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International Research HighlightWeight loss surgery may reduce heart disease risk
February 10, 2019
Data suggests gastric bypass surgery reduces by half the risk of developing congestive heart failure.
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International Research HighlightA viral vector to fall back on
February 10, 2019
A highly efficient method for delivering genetic materials to the spinal cord may help in the treatment of an inherited muscle-wasting disease.
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International Research HighlightMining big data highlights importance of ‘junk DNA’
February 10, 2019
An exploratory bioinformatics investigation suggests ‘junk DNA’ plays a critical role in early embryonic development and species evolution.
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International Research HighlightInjury prevention could stem opioid abus
February 10, 2019
People are 1.4 times more likely to become persistent users of opioid painkillers after suffering a traumatic injury.
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International Research HighlightFilling in the microbial gaps
February 10, 2019
A new survey of the microbiome offers insights into its diversity and the interplay between bacteria and their human hosts.
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International Research HighlightA personalized prescription for cancer treatment
February 9, 2019
'Mini organ' technique provides insight into the molecular basis of bowel cancer, and hope for future treatment.
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International Research HighlightTumours activate neurons to trigger appetite loss
February 7, 2019
Blocking a population of neurons in the brain could help treat anorexia and weight loss caused by cancer.
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International Research HighlightExercising young protects heart later in life
February 6, 2019
Exercising when young can greatly reduce the risk of developing ischaemic heart disease in adulthood.
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International Research HighlightHope for holding back hyperglycaemia
February 6, 2019
A two-drug combination that preserves and stimulates pancreatic function could offer a new option for treating type I diabetes.
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International Research HighlightAntibody could have dual role
January 30, 2019
An antibody that blocks the effect of follicle stimulating hormone may simultaneously treat obesity and osteoporosis.
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International Research HighlightExposure to ‘nonstick’ chemical risky for foetal health
January 20, 2019
Maternal exposure to chemicals widely used in consumer products and industries disrupts steroid hormone levels in babies’ cord blood.
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International Research HighlightZeroing in on risk factors for pancreatic cancer
January 20, 2019
Large gene databases help researchers discern lifestyle traits that cause pancreatic cancer.
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International Research HighlightNanomedicine: A two-headed force against lung cancer
January 16, 2019
Nanocarriers that can transport precise doses of two drugs may prove effective against lung tumours.
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International Research HighlightBrain training at home helps multiple sclerosis
January 16, 2019
Cognitive impairment caused by multiple sclerosis can be improved with a computer-based brain-training system accessible at home.
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International Research HighlightIschemic stroke: Examining brain inflammation
January 9, 2019
Scientists in Japan identify a signalling pathway that may provide a target for reducing inflammation in the brain following ischemic stroke.
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International Research HighlightRunning sensors on patient power
October 8, 2017
Sensors that generate electricity from the digestive tract may enable long-term monitoring of patient health.
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International Research HighlightDetermining the roots of derailed development
September 23, 2017
Mutational profiling allows researchers to home in on a protein domain with a critical role in human neurological development.
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International Research HighlightHope for restoring immune defenses in hepatitis
September 20, 2017
Antioxidants might reverse changes in immune cells that allow hepatitis B virus to persist.
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International Research HighlightGrape-derived antiviral drug could treat MERS
September 10, 2017
Initial investigations show an antiviral drug, derived from grape and cranberry plants, could also be effective against the virus that causes MERS.
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International Research HighlightDemystifying a diet to live by
August 21, 2017
A new connection is found between sensory neurons, diet and longevity.
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International Research HighlightUnderstanding a neurological disease via the drugs that treat it
July 13, 2017
Novel antibacterial properties in existing multiple sclerosis treatments hint at a possible cause of the disease.
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International Research HighlightGene mutations linked to spread of colorectal cancer
July 10, 2017
Test could identify colorectal cancer patients with most to gain from chemotherapy.
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International Research HighlightGoing with the flow in brain mapping
July 9, 2017
Recording changes in cerebral blood flow makes mapping active brain areas possible during visual stimulation.
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International Research HighlightClamping down on post-stroke infections
June 10, 2017
Specialized cells that impair the immune system after a stroke could be targeted to protect patients from infection.
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International Research HighlightWidening the net
June 9, 2017
A novel strategy seeks therapeutic targets in cancers by examining the genes retained in their genomes.
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International Research HighlightRaising the bar for gene therapy tests
June 7, 2017
Researchers develop a strategy to improve contamination detection in gene-doping tests.
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International Research HighlightBeta cell boost could replace insulin injections
February 28, 2017
A strategy for deriving beta cells from patients with type I diabetes could transform disease treatment.
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International Research HighlightConcerns raised about digoxin safety
January 15, 2017
A drug commonly used to treat heart failure could be associated with an increased risk of death in certain patient groups.
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International Research HighlightRadiolabeled peptides could monitor diabetes progression
January 9, 2017
Radioactive peptides effectively image insulin-producing cells, with potential to chart disease progression in diabetes.
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International Research HighlightPowerful tool invented to probe entire human proteome
January 4, 2017
The technology could give the search for new drugs, especially for cancer and terminal diseases, a significant boost.
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International Research HighlightTargeting cancer through the skin
January 1, 2017
More medicines could soon be delivered through the skin by cargo-carrying peptides.
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International Research HighlightChinese herbal remedies yield anti-cancer drug leads
December 20, 2016
A shortlist of Chinese medicinal plants containing the most anti-cancer compounds could yield new drugs for patients.
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International Research HighlightHepatitis B: Predict, treat, avoid
December 16, 2016
A biomarker has been found that can help predict the reactivation of the hepatitis B virus in immunosuppressed patients.
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International Research HighlightGo Mediterranean for cancer protection
December 10, 2016
A Mediterranean diet reduces the risk of colorectal cancer by half in Italy.
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International Research HighlightScrutinizing cellular bonds in heart failure patients
December 6, 2016
Atomic force microscopy can help scientists identify which chronic heart failure patients are more likely to suffer complications.
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International Research HighlightShedding light on tumours
December 6, 2016
A contrast agent, containing nanoparticles that are sensitive to acidity, lights up solid tumours on magnetic resonance imaging scans.
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International Research HighlightHoning in on thyroid cancer
December 3, 2016
A closer look at gene expression in papillary thyroid cancer opens new opportunities for its detection.
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International Research Highlight‘Young blood’ a defence against infection
December 2, 2016
Signatures of a more potent and durable immune response may explain why children fend off chronic hepatitis C infection better than adults.
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International Research HighlightReaching for success is easier for the tall
November 30, 2016
A broad survey of British men and women suggests hereditary differences in height and weight affect prospects for socioeconomic positioning.
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International Research HighlightThe genetics of smoking behaviour and lung disease
November 29, 2016
Samples reveal specific genetic signals that determine a person’s risk for tobacco addiction and lung damage from smoking.
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International Research HighlightObesity surgery can also resolve diabetes
November 22, 2016
Large-scale study shows bariatric surgery helps keep weight down and can resolve diabetes and hypertension.
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International Research HighlightHow hepatitis C takes control
November 2, 2016
The hepatitis virus commandeers key cellular machinery to keep itself safe.
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International Research HighlightMaking room for regeneration
November 1, 2016
Drugs that prevent the accumulation of scar-forming molecules could facilitate nerve repair in multiple sclerosis and other disorders.
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International Research HighlightHepatitis B poses lifetime cancer risk
August 14, 2016
Clearance of active hepatitis B virus from the blood does not reduce the risk of liver cancer.
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International Research HighlightUnmaking a muscle
August 14, 2016
The ‘missing links’ in a process that drives muscle wasting in heart failure patients may offer promising drug targets.
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International Research HighlightFirst MERS autopsy yields ‘critical insights’
August 14, 2016
The world’s first autopsy of a patient with Middle East respiratory syndrome shows that the lungs are the infection’s main target.
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International Research HighlightNew probe shines light inside arteries
August 14, 2016
A new design of catheter probe reveals complete, detailed pictures of fat deposits inside arteries for the first time.
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International Research HighlightSilkworms’ sweet success
August 14, 2016
Silkworms could point toward a new preventative therapy for type II diabetes.
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International Research HighlightThe metabolomics revolution
August 14, 2016
Understanding the body’s metabolic profile is transforming drug discovery and personalized medicine.
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International Research HighlightThe hunt for dementia’s molecular triggers
August 14, 2016
Gender differences provide molecular clues for scientists seeking better ways to treat dementia.
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International Research HighlightA protective coat for nanoparticles
August 14, 2016
Nanoparticles coated in a ‘don’t-eat-me’ protein can evade the body’s immune system, improving chances of successful drug delivery.
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International Research HighlightPromising protein target
August 11, 2016
A structural analysis of proteins in the Middle East Respiratory Syndrome virus reveals a promising new target for treatments.
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International Research HighlightHow hepatitis C takes control
August 11, 2016
The hepatitis virus commandeers key cellular machinery to keep itself safe.
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International Research HighlightDrug study shines new light on receptors
August 11, 2016
Identifying the binding site of an antagonist is expected to transform the treatment of diabetes and other metabolic diseases.
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International Research HighlightMaking room for regeneration
August 11, 2016
Drugs that prevent the accumulation of scar-forming molecules could facilitate nerve repair in multiple sclerosis and other disorders.
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International Research HighlightLatest technique delivers CRISPR gene screens
August 11, 2016
A comparison of gene editing techniques reveals benefits of latest technology over conventional approach.
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International Research HighlightDrug-carrying nanoparticles not reaching targets
August 11, 2016
The targeted delivery of drug-carrying nanoparticles to solid tumours needs improvement before it can be effective in humans.
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International Research HighlightTracking the effects of therapeutic genes
August 11, 2016
Targeted nanoparticles offer hope of better methods for tracking the effects of gene therapy.
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International Research HighlightThe truth about fatty acids
August 11, 2016
A Dutch cohort study shows that saturated fatty acids might not be as bad as people think.
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International Research HighlightReversing immune decline
August 10, 2016
Targeting a certain gene could help promote healthy aging.